Objective: To conduct a comprehensive bioclimatic assessment of meteorological conditions in health resort area and to evaluate the efficacy of resort-based therapy in patients with ischemic heart disease (IHD).

Materials and methods. The study analyzed the bioclimatic potential of the “Krinitsa” Health Resort (Zhdanovichi, Minsk District, Minsk Region, Republic of Belarus) based on the archival meteorological data from 2020 to 2025. The pathophysiological impact of these factors on changes in the subjective symptoms of 50 IHD patients was evaluated during a 14-day resort- based rehabilitation course in the winter. Climatotherapy programs for IHD patients were optimized using digital technologies.

Results. The comprehensive bioclimatic assessment revealed that meteorological conditions impose a high stress on IHD patients during winter, whereas spring, autumn, and summer offer favorable conditions. The study showed that a moderate temperature regime (equivalent effective temperature +22.3°C), low annual temperature variability (annual amplitude 23.0°C), and consistently high relative humidity (78%) facilitated by hydro-air ionization from a nearby body of water have pronounced cardioprotective and sedative effects. Analysis of the efficacy of resort-based climatotherapy demonstrated a highly significant, differentiated regression of symptoms (p<0.001): the resolution of cardiac pain (Day 2, with 2% episodes on Day 10), dyspnea (Day 3), arrhythmic syndrome (Day 4), and anginal pain (by Day 11).

Conclusion. A statistically significant therapeutic value of the proposed automated approach was revealed for all evaluated signs and a highly significant linear regression of the main pathological syndromes in IHD patients was recorded. Digitalizing climatotherapy programs via a mobile application will enable the management of predicted risks regarding IHD exacerbation.

Objective: To comparatively analyze the recovery period and evaluate the efficacy of rehabilitation measures in women following postpartum hemorrhage and hemostasis via Hayman and B-Lynch compression suturing.

Material and methods. This prospective study included 84 patients who experienced postpartum hemorrhage. The women were divided into two groups: Group 1 consisted of 32 patients managed with the B-Lynch suture, and Group 2 comprised 52 patients managed with the Hayman suture. Follow-up evaluations included ultrasound, office hysteroscopy, and hormonal profile assessments at 1, 3, and 6 months.

Results. Ultrasonography revealed faster uterine involution in Group 2, with a cavity size of 12.9±0.9 mm at days 3–5 versus 16.5±0.8 mm in Group 1 (p=0.002). Endometrial thickness in Group 2 significantly exceeded that of Group 1 at 1 month (3.6±0.3 versus 2.1±0.4 mm; p=0.002), and at 3 months (6.1±0.4 versus 4.5±0.5 mm; p=0.012). Hysteroscopy confirmed the complete absence of intrauterine adhesions in Group 2, whereas Asherman’s syndrome was noted in 6 (18.75%) Group 1 patients (p=0.002).

Conclusion. The standard postpartum rehabilitation regimen demonstrates significantly higher efficacy in women following the Hayman suture compared to the B-Lynch suture. The less invasive nature of the Hayman technique accelerates uterine involution while promoting earlier endometrial regeneration and menstrual cycle restoration.

Background. The prevalence of gastroesophageal reflux disease (GERD) in the population is 11.5–23.5%. Despite modern pharmacotherapy options, up to 50% of GERD patients continue to experience reflux-related symptoms, which significantly impairs their quality of life and can lead to serious complications. The insufficient effectiveness of existing therapeutic strategies requires optimized approaches to managing such patients. Enhancing GERD control is possible by incorporating drinking balneotherapy into the standard treatment regimen.

Objective: To provide a rationale for and evaluate the effectiveness of including Uvinskaya mineral water in the medical rehabilitation regimen for patients with non-erosive reflux disease (NERD).

Material and methods. The study evaluated 100 NERD patients and 30 healthy controls without complaints or registered illnesses. The NERD patients were randomly divided into two subgroups of 50 each. Subgroup 1 received standard NERD therapy (omeprazole 20 mg twice daily, itopride 50 mg three times daily) in combination with Uvinskaya mineral water for 1 month; Subroup 2 received standard therapy alone for the same duration. During the 6-month follow-up, the following evaluations were performed in the compared subgroups: clinical data analysis, patient surveys using using the GastroEsopha- geal Reflux Disease Questionnaire (GERDQ) and the (Gastrointestinal Symptom Rating Scale (GSRS), 24-hour pH-impedance monitoring, esophagogastroduodenoscopy, and measurements of serum motilin and gastrin levels.

Results. After 1 month of follow-up, substantial improvements were noted in all evaluated parameters in the compared subgroups, with no significant differences. By month 3, this positive trend persisted in Subgroup 1, while the parameters in Subgroup 2 began to approach baseline values. By month 6, the outcomes in the balneotherapy subgroup converged with those in the standard therapy subgroup, with the exception of the esophageal endoscopic findings: signs of esophagitis were observed half as frequently in patients who drank Uvinskaya mineral water.

Conclusion. The inclusion of Uvinskaya mineral water in the treatment and rehabilitation program for NERD helps prolong its clinical benefits. The clinical efficacy of a course of balneotherapy with this mineral water is confirmed by persistent positive changes in 24-hour esophageal pH-impedance monitoring. Furthermore, the endoscopic improvements objectively reflect the therapeutic effectiveness of this approach.

Objective: To provide a theoretical and experimental basis for using health-enhancing physical activity to improve the functional and reserve capacities of the organism of 11- to 12-year-old schoolchildren, while accounting for the types of autonomic heart rate regulation.

Material and methods. The study involved 60 fifth-grade boys (11–12 years old) from School No. 32 in Togliatti; these children were divided into an intervention group (IG, n=30) and a control group (CG, n=30). Over a 6-month period, the IG participated in a type-specific corrective and developmental exercise program. This regimen included tailored exercises routines designed for each of the four types of autonomic regulation (I – moderate sympathicotonia; II – severe sympathicotonia; III – normotonia; IV – vagotonia). The CG followed the standard school curriculum supplemented with sports games. Functional assessment included heart rate variability (HRV) analysis, as well as the evaluation of functional reserves, oxygen saturation, and the maximum hypoxic index. Measurements were carried out at baseline and at the end of the experiment.

Results. At baseline, both groups exhibited low functional reserves (65–74% of the expected value), reduced oxygen saturation (93–94%), and low hypoxic resistance. After 6 months of training, the IG showed significant improvements across all metrics, which shifted to the average range: functional reserves increased to 75–85%, saturation reached 95–96%, and the hypoxic index improved to average values (75–85% efficiency level). Conversely, the CG showed no significant changes: all metrics remained at their initially low levels. Differences between IG and CG at end of the experiment were statistically significant (p<0.05).

Conclusion. Implementing an individualized approach based on HRV analysis which features tailored physical workloads matching each type of autonomic regulation is effective in increasing the functional reserves of schoolchildren. Conversely, the standard physical education program does not yield significant improvements. The value of health-enhancing physical activity lies in personalized health management, where exercise workloads provide a controlled training stimulus to restore regulatory mechanisms and prevent maladaptive states.

Background. Falls affect approximately one in three individuals aged over 65 annually, thus ranking as a leading cause of injury and functional decline. Dual-task training (DTT) is recognized as a promising non-pharmacological method for preventing falls. Although systematic reviews up to 2022 confirmed its benefits, they did not examine the relationship between clinical effect and dosing parameters.

Objective: To evaluate DTT in preventing falls and improving postural balance among the elderly (≥60 years) using a systematic review of publications from 2022–2026 with quantitative synthesis of randomized controlled trial (RCT) data, and to conduct an exploratory meta-regression with training protocol parameters as moderators.

Material and methods. A systematic review was conducted on publications from the PubMed/MEDLINE, Embase, PEDro, Web of Science, Google Scholar, eLibrary, and CyberLeninka databases from January 1, 2022, to February 28, 2026. The inclusion criteria were as follows: RCTs for quantitative synthesis; systematic reviews and meta-analyses for narrative synthesis on virtual reality in DTT; participants aged ≥60 years; assessment of primary outcomes using the Berg Balance Scale (BBS) and Timed Up and Go (TUG) tests; and availability of data on fall incidence. The PRISMA 2020 methodology was applied. The Cochrane Risk of Bias 2 tool, the DerSimonian–Laird random effects model, and the exploratory meta-regression method were used (k=5).

Results. A total of 38 publications included 22 RCTs, 16 systematic reviews and meta-analyses. Five RCTs with complete numerical data (PEDro ≥6/10) were selected for quantitative pooling. The pooled standardized mean difference for BBS was 0.61 (95% confidence interval (CI) 0.46…0.76), I2=0%. The mean difference for TUG was –2.2 s (95% CI –2.8...–1.6), I2=14%. Meta- analysis for the fall rate was not feasible (1 RCT: risk ratio 0.56; 95% CI 0.38…0.82). Meta-regression did not reveal statistically significant effects of dose parameters (k=5, power <40%).

Conclusion. DTT improves postural balance, though the effect is moderate. RCTs with complete dose reporting should be conducted to confirm dose-response relationships.

The fascial system is a complex connective tissue network that provides structural integrity, mobility, and sensory innervation of the body. Despite the high prevalence of fascial disorders (chronic back pain, myofascial pain syndrome, and fibromyalgia), their pathogenesis remains insufficiently understood, and current therapeutic strategies are not always effective. Therefore, a need exists to synthesize contemporary data on the anatomy, histology, pathophysiology, and theoretical models of the fascial system, while critically evaluating treatment methods for fascial pathology. This review presents information on the anatomical and histological structure, as well as the functional heterogeneity, of fascia. Three theoretical models are analyzed: biotensegrity, mechanotransduction, and myofascial chains. The study examines key pathophysiological mechanisms, including myofibroblast activation, ischemia, acidosis, hyaluronan depolymerization, and peripheral and central sensitization. It also systematizes various treatment methods such as manual therapy, physical exercise, dry needling, acupuncture, shockwave therapy, and pharmacotherapy (including nonsteroidal anti-inflammatory drugs, glucocorticosteroids, local anesthetics, and muscle relaxants), alongside rehabilitation approaches. The findings may be of value for rheumatologists, orthopedists, neurologists, and physical rehabilitation specialists.

Autism spectrum disorders (ASDs) represent a heterogeneous group of neurodevelopmental conditions. Diagnosis and treatment of autism carry high social significance, necessitating the development of effective rehabilitation strategies. Artificial intelligence (AI) technologies offer fundamentally new opportunities to personalize rehabilitation interventions in ASD. This comprehensive review examines key directions for AI integration into clinical practice: enhancing diagnostic objectivity through digital phenotyping, predicting individual developmental trajectories and treatment responses, and designing adaptive therapeutic systems. Particular attention is paid to AI-assisted technologies for developing social communication skills, including virtual reality and social robotics. Meta-analytic data confirm the clinical utility of AI technologies, showing moderate-to-large effects for social communication, emotion recognition, and adaptive skills. Naturalistic developmental behavioral interventions, combined with augmentative and alternative communication technologies have been shown to demonstrate sustained improvements in spontaneous communication in minimally verbal patients. The review discusses prospects for personalizing interventions based on physiological monitoring data and prognostic modeling along with the role of telehealth technologies and intelligent family support systems. Critical challenges of AI system implementation are analyzed, ranging from privacy risks to the translational gap between research and clinical practice. Overall, maximizing the potential of AI in ASD rehabilitation requires a balanced approach combining accurate and explainable algorithms, inclusive user design, and interdisciplinary collaboration with active involvement of autistic individuals and their families at all stages of frontier technology development and implementation.

Objective: To summarize contemporary data on the use of biofeedback (BFB) in medical rehabilitation of patients following musculoskeletal surgery, evaluate the capabilities of various methods, and identify promising directions for their future application.

Material and methods. A scientific literature review was conducted across PubMed/MEDLINE, Google Scholar, and eLibrary databases. The analysis examined 34 studies published between 2013 and 2026, including original clinical studies, randomized controlled trials, systematic reviews, and meta-analyses. This review focused on the application of electromyographic and biomechanical BFB, stabilometric training, load distribution monitoring systems, and modern digital technologies following major joint replacement, arthroscopic interventions, and anterior cruciate ligament reconstruction.

Results. BFB techniques enable objective monitoring of muscle activity, weight distribution, postural stability, and movement parameters. Electromyographic and stabilometric BFB are the most widely investigated. Several studies demonstrate improvements in muscle activation, weight-bearing symmetry, postural balance, and individual gait parameters when BFB is incorporated into rehabilitation programs. However, not all studies report advantages over standard rehabilitation. Differences in the technologies used, clinical groups, and training protocols (initiation timing and duration) confound the comparison of results.

Conclusion. BFB techniques can be used to complement comprehensive rehabilitation following musculoskeletal surgery. The choice of a method should be based on the patient's primary functional impairment. Further clinical studies evaluating long- term functional outcomes are needed to determine the optimal timing, duration, and parameters of BFB application.