rehabРеабилитологияJournal of Medical Rehabilitation2949-58732949-5881IRBIS LLC10.17749/2949-5873/rehabil.2025.48rehab-62Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL ARTICLESВозвращение женщин, получавших разные программы реабилитации после хирургического лечения ранних стадий онкогинекологических заболеваний, к трудовой деятельности: результаты проспективного лонгитюдного исследования с рандомизацией на исходном визитеReturn to work in patients undergoing different rehabilitation programs following surgical treatment of early-stage female cancers: results of a prospective longitudinal study with randomization at baselinehttps://orcid.org/0000-0002-3367-9844БлиновД. В.BlinovD. V.

Блинов Дмитрий Владиславович, к.м.н.

WoS ResearcherID: E-8906-2017

Scopus Author ID: 6701744871

Лялин пер., д. 11-13/1, Москва 101000

Алтуфьевское ш., д. 37А, стр. 1, Москва 127410

ул. 2-я Брестская, д. 5, стр. 1-1а, Москва 123056

Dmitry V. Blinov, PhD, MBA

WoS ResearcherID: E-8906-2017

Scopus Author ID: 6701744871

11-13/1 Lyalin Passage, Moscow 101000

37А bldg 1 Altufyevskoe Shosse, Moscow 127410

5 bldg 1-1a 2nd Brestskaya Str., Moscow 123056

blinov2010@googlemail.ruhttps://orcid.org/0000-0002-7456-2386СолоповаА. Г.SolopovaA. G.

Солопова Антонина Григорьевна, д.м.н., проф.

WoS ResearcherID: Q-1385-2015

Scopus Author ID: 6505479504

ул. Трубецкая, д. 8/2, Москва 119048

Antonina G. Solopova, Dr. Sci. Med., Prof.

WoS ResearcherID: Q-1385-2015

Scopus Author ID: 6505479504

8/2 Trubetskaya Str., Moscow 119048

https://orcid.org/0000-0002-6619-6179ГалкинВ. Н.GalkinV. N.

Галкин Всеволод Николаевич, д.м.н., проф.

Коломенский пр-д, д. 4, Москва 115446

Vsevolod N. Galkin, Dr. Sci. Med., Prof.

4 Kolomensky Dr., Moscow 115446

https://orcid.org/0000-0003-1115-3144ИвановА. Е.IvanovA. E.

Иванов Александр Евгеньевич, к.м.н.

Коломенский пр-д, д. 4, Москва 115446

Aleksandr E. Ivanov, PhD

4 Kolomensky Dr., Moscow 115446

https://orcid.org/0009-0006-2166-2574АкавоваС. А.AkavovaS. A.

Акавова Саида Абдулкадыровна

Коломенский пр-д, д. 4, Москва 115446

Saida A. Akavova

4 Kolomensky Dr., Moscow 115446

Институт Превентивной и Социальной Медицины; Федеральное государственное бюджетное учреждение «Федеральный научно-клинический центр медицинской реабилитации и курортологии Федерального медико-биологического агентства»; Автономная некоммерческая организация дополнительного профессионального образования «Московский медико-социальный институт им. Ф.П. Гааза»РоссияInstitute for Preventive and Social Medicine; Federal Scientific and Clinical Center for Medical Rehabilitation and Balneology of the Federal Medical and Biological Agency; Moscow Haass Medical Social InstituteRussian FederationФедеральное государственное автономное образовательное учреждение высшего образования «Первый Московский государственный медицинский университет им. И.М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский Университет)РоссияSechenov UniversityRussian FederationГосударственное бюджетное учреждение здравоохранения г. Москвы «Городская клиническая больница им. С.С. Юдина Департамента здравоохранения г. Москвы»РоссияYudin City Clinical HospitalRussian Federation20252406202531513Copyright © Блинов Д.В., Солопова А.Г., Галкин В.Н., Иванов А.Е., Акавова С.А., 20252025Блинов Д.В., Солопова А.Г., Галкин В.Н., Иванов А.Е., Акавова С.А.Blinov D.V., Solopova A.G., Galkin V.N., Ivanov A.E., Akavova S.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rehabilitology.com/jour/article/view/62Введение

Введение. Хирургическое лечение остается основным методом радикальной терапии онкогинекологических заболеваний на ранних стадиях, однако оно может сопровождаться обусловленными постовариоэктомическим синдромом и дистрессом осложнениями, включая сексуальную дисфункцию, физические и психосоциальные расстройства, что негативно влияет на качество жизни и профессиональную активность пациенток. Это определяет необходимость разработки эффективных реабилитационных стратегий, направленных на восстановление трудоспособности после лечения.

Цель

Цель: оценить влияние различных программ реабилитации на возвращение к трудовой деятельности у пациенток после хирургического лечения ранних стадий рака шейки матки (РШМ) и рака эндометрия (РЭ).

Материал и методы

Материал и методы. В проспективное лонгитюдное исследование включены 164 взрослые женщины 18 лет и старше с раком шейки матки (РШМ) IА/IB стадий и раком эндометрия (РЭ) I/II стадий. Пациентки были разделены на следующие группы: РШМ-1 (n=51) и РЭ-1 (n=29) – прошедшие полный курс комплексной «активной» реабилитации, включающей коррекцию образа жизни, физиотерапию, психологическую поддержку и другие вмешательства в течение 12 мес после радикального хирургического лечения; РШМ-2 (n=52) и РЭ-2 (n=32) – получавшие рекомендации в соответствии с актуальными на момент набора в исследование клиническими рекомендациями, т.е. в «пассивном» режиме. Катамнез оценивали на 24-м и 36-м месяцах после операции.

Результаты

Результаты. В группах, получавших комплексную «активную» реабилитацию, возвращение к трудовой деятельности происходило быстрее, чем у проходивших реабилитацию в «пассивном» режиме, начиная с 3-го месяца наблюдения. Через 36 мес после хирургического вмешательства возвратились к трудовой деятельности все пациентки из группы РШМ-1 и 90,9% пациенток из группы РЭ-1, тогда как в группе РШМ-2 – лишь 66,7%, а в группе РЭ-2 – 55,6%. Шансы возвращения к профессиональной активности в группах РШМ-1 и РЭ-1 были достоверно выше, чем в РШМ-2 и РЭ-2 (ОШ 0,467; 95% ДИ 0,309–0,706; p<0,001 против ОШ 0,548; 95% ДИ 0,440–0,684; p<0,001 соответственно).

Заключение

Заключение. Персонализированные комплексные реабилитационные программы значительно повышают вероятность восстановления трудоспособности и ускоряют его у пациенток после хирургического лечения онкогинекологических заболеваний. Полученные данные подтверждают важность комплексной «активной» реабилитации для социальной реинтеграции и улучшения исходов в долгосрочной перспективе. Дальнейшие исследования должны быть направлены на оптимизацию компонентов таких программ и их внедрение в реальную клиническую практику.

Background

Background. Surgical treatment remains the primary method of radical therapy for early-stage female cancers. However, it may be accompanied by complications associated with post-ovariectomy syndrome and distress. These complications, including sexual dysfunction as well as physical and psychosocial disorders, negatively impact patients’ quality of life and professional activity, which highlights the need to develop effective rehabilitation strategies aimed at restoring working capacity after treatment.

Objective

Objective: To assess the impact of different rehabilitation programs on the return to work among female patients following surgical treatment for early-stage cervical cancer (CC) and endometrial cancer (EC).

Material and methods

Material and methods. A prospective longitudinal study included 164 adult women aged 18 years and older with stage IA/IB CC and stage I/II EC. The patients were divided into the following groups: CC-1 (n=51) and EC-1 (n=29) – who underwent a full course of comprehensive "active" rehabilitation, including lifestyle modification, physiotherapy, psychological support, and other interventions within 12 months after radical surgical treatment; CC-2 (n=52) and EC-2 (n=32) – who underwent a "passive" rehabilitation, i.e., received recommendations in accordance with the current clinical guidelines at the time of study enrollment. Follow-up was performed at 24 and 36 months following surgery.

Results

Results. In the groups that underwent comprehensive "active" rehabilitation, patients returned to work earlier compared to those undergoing "passive" rehabilitation, starting from the third month of follow-up. At 36 months after surgery, all patients in the CC-1 group and 90.9% of patients in the EC-1 group returned to work, whereas only 66.7% in the CC-2 group and 55.6% in the EC-2 group returned. The likelihood of returning to professional activity was significantly higher in the CC-1 and EC-1 groups compared to the CC-2 and EC-2 groups (OR 0.467, 95% CI 0.309–0.706, p<0.001 vs. OR 0.548, 95% CI 0.440–0.684, p<0.001, respectively).

Conclusion

Conclusion. Personalized comprehensive rehabilitation programs significantly increase the likelihood of recovery of work capacity and accelerate this process in female patients following surgical treatment of gynecologic cancers. The findings support the importance of comprehensive "active" rehabilitation for social reintegration and improved long-term outcomes. Further research should focus on optimizing the components of such programs and integrating them into routine clinical practice.

рак шейки маткирак эндометриярак тела маткиреабилитациявозврат к трудуcervical cancerendometrial canceruterine cancerrehabilitationreturn to workReferencesMahantshetty U., Lavanya G., Grover S., et al. Incidence, treatment and outcomes of cervical cancer in low- and middle-income countries. Clin Oncol. 2021; 33 (9): e363–71. https://doi.org/10.1016/j.clon.2021.07.001.Mahantshetty U., Lavanya G., Grover S., et al. Incidence, treatment and outcomes of cervical cancer in low- and middle-income countries. Clin Oncol. 2021; 33 (9): e363–71. https://doi.org/10.1016/j.clon.2021.07.001.Hull R., Mbele M., Makhafola T., et al. Cervical cancer in low and middle-income countries. Oncol Lett. 2020; 20 (3): 2058–74. https://doi.org/10.3892/ol.2020.11754.Hull R., Mbele M., Makhafola T., et al. Cervical cancer in low and middle-income countries. Oncol Lett. 2020; 20 (3): 2058–74. https://doi.org/10.3892/ol.2020.11754.Van Christ Manirakiza A., Pfaendler K.S. Breast, ovarian, uterine, vaginal, and vulvar cancer care in low-and middle-income countries: prevalence, screening, treatment, palliative care, and human resources training. Obstet Gynecol Clin North Am. 2022; 49 (4): 783–93. https://doi.org/10.1016/j.ogc.2022.08.004.Van Christ Manirakiza A., Pfaendler K.S. Breast, ovarian, uterine, vaginal, and vulvar cancer care in low-and middle-income countries: prevalence, screening, treatment, palliative care, and human resources training. Obstet Gynecol Clin North Am. 2022; 49 (4): 783–93. https://doi.org/10.1016/j.ogc.2022.08.004.Salehiniya H., Allahqoli L., Momenimovahed Z. Risk factors for endometrial cancer in the world: a narrative review of the recent literature. Clin Exp Obstet Gynecol. 2024; 51 (7): 169. https://doi.org/10.31083/j.ceog5107169.Salehiniya H., Allahqoli L., Momenimovahed Z. Risk factors for endometrial cancer in the world: a narrative review of the recent literature. Clin Exp Obstet Gynecol. 2024; 51 (7): 169. https://doi.org/10.31083/j.ceog5107169.Dring J.C., Forma A., Chilimoniuk Z., et al. Essentiality of trace elements in pregnancy, fertility, and gynecologic cancers – a state-of-the-art review. Nutrients. 2021; 14 (1): 185. https://doi.org/10.3390/nu14010185.Dring J.C., Forma A., Chilimoniuk Z., et al. Essentiality of trace elements in pregnancy, fertility, and gynecologic cancers – a state-of-the-art review. Nutrients. 2021; 14 (1): 185. https://doi.org/10.3390/nu14010185.Singh D., Vignat J., Lorenzoni V., et al. Global estimates of incidence and mortality of cervical cancer in 2020: a baseline analysis of the WHO Global Cervical Cancer Elimination Initiative. Lancet Glob Health. 2023; 11 (2): e197–206. https://doi.org/10.1016/S2214-109X(22)00501-0.Singh D., Vignat J., Lorenzoni V., et al. Global estimates of incidence and mortality of cervical cancer in 2020: a baseline analysis of the WHO Global Cervical Cancer Elimination Initiative. Lancet Glob Health. 2023; 11 (2): e197–206. https://doi.org/10.1016/S2214-109X(22)00501-0.Howard B. Why is cervical cancer still killing thousands of women a year? Available at: https://www.prevention.com/health/health-conditions/a44798697/cervical-cancer-still-kills-thousands-of-women/ (accessed 12.12.2024).Howard B. Why is cervical cancer still killing thousands of women a year? Available at: https://www.prevention.com/health/health-conditions/a44798697/cervical-cancer-still-kills-thousands-of-women/ (accessed 12.12.2024).Paleari L., Pesce S., Rutigliani M., et al. New insights into endometrial cancer. Cancers. 2021; 13 (7): 1496. https://doi.org/10.3390/cancers13071496.Paleari L., Pesce S., Rutigliani M., et al. New insights into endometrial cancer. Cancers. 2021; 13 (7): 1496. https://doi.org/10.3390/cancers13071496.Gu B., Shang X., Yan M., et al. Variations in incidence and mortality rates of endometrial cancer at the global, regional, and national levels, 1990–2019. Gynecol Oncol. 2021; 161 (2): 573–80. https://doi.org/10.1016/j.ygyno.2021.01.036.Gu B., Shang X., Yan M., et al. Variations in incidence and mortality rates of endometrial cancer at the global, regional, and national levels, 1990–2019. Gynecol Oncol. 2021; 161 (2): 573–80. https://doi.org/10.1016/j.ygyno.2021.01.036.Smrz S.A., Calo C., Fisher J.L., Salani R. An ecological evaluation of the increasing incidence of endometrial cancer and the obesity epidemic. Am J Obstet Gynecol. 2021; 224 (5): 506.e1–8. https://doi.org/10.1016/j.ajog.2020.10.042.Smrz S.A., Calo C., Fisher J.L., Salani R. An ecological evaluation of the increasing incidence of endometrial cancer and the obesity epidemic. Am J Obstet Gynecol. 2021; 224 (5): 506.e1–8. https://doi.org/10.1016/j.ajog.2020.10.042.Kalampokas E., Giannis G., Kalampokas T., et al. Current approaches to the management of patients with endometrial cancer. Cancers. 2022; 14 (18): 4500. https://doi.org/10.3390/cancers14184500.Kalampokas E., Giannis G., Kalampokas T., et al. Current approaches to the management of patients with endometrial cancer. Cancers. 2022; 14 (18): 4500. https://doi.org/10.3390/cancers14184500.Uwins C., Patel H., Prakash Bhandoria G., et al. Laparoscopic and robotic surgery for endometrial and cervical cancer. Clin Oncol. 2021; 33 (9): e372–82. https://doi.org/10.1016/j.clon.2021.05.001.Uwins C., Patel H., Prakash Bhandoria G., et al. Laparoscopic and robotic surgery for endometrial and cervical cancer. Clin Oncol. 2021; 33 (9): e372–82. https://doi.org/10.1016/j.clon.2021.05.001.D'Augè T.G., Giannini A., Bogani G., et al. Prevention, screening, treatment and follow-up of gynecological cancers. State of art and future perspectives. Clin Exp Obstet Gynecol. 2023; 50 (8): 160. https://doi.org/10.31083/j.ceog5008160.D'Augè T.G., Giannini A., Bogani G., et al. Prevention, screening, treatment and follow-up of gynecological cancers. State of art and future perspectives. Clin Exp Obstet Gynecol. 2023; 50 (8): 160. https://doi.org/10.31083/j.ceog5008160.Baker-Rand H., Kitson S.J. Recent advances in endometrial cancer prevention, early diagnosis and treatment. Cancers. 2024; 16 (5): 1028. https://doi.org/10.3390/cancers16051028.Baker-Rand H., Kitson S.J. Recent advances in endometrial cancer prevention, early diagnosis and treatment. Cancers. 2024; 16 (5): 1028. https://doi.org/10.3390/cancers16051028.Jing H., Xiuhong W., Ying Y., et al. Complications of radical hysterectomy with pelvic lymph node dissection for cervical cancer: a 10-year single-centre clinical observational study. BMC Cancer. 2022; 22 (1): 1286. https://doi.org/10.1186/s12885-022-10395-9.Jing H., Xiuhong W., Ying Y., et al. Complications of radical hysterectomy with pelvic lymph node dissection for cervical cancer: a 10-year single-centre clinical observational study. BMC Cancer. 2022; 22 (1): 1286. https://doi.org/10.1186/s12885-022-10395-9.Plante M., Kwon J.S., Ferguson S., et al. Simple versus radical hysterectomy in women with low-risk cervical cancer. New Engl J Med. 2024; 390 (9): 819–29. https://doi.org/10.1056/NEJMoa2308900.Plante M., Kwon J.S., Ferguson S., et al. Simple versus radical hysterectomy in women with low-risk cervical cancer. New Engl J Med. 2024; 390 (9): 819–29. https://doi.org/10.1056/NEJMoa2308900.Hassan H., Allen I., Sofianopoulou E., et al. Long-term outcomes of hysterectomy with bilateral salpingo-oophorectomy: a systematic review and meta-analysis. Am J Obstet Gynecol. 2024; 230 (1): 44–57. https://doi.org/10.1016/j.ajog.2023.06.043.Hassan H., Allen I., Sofianopoulou E., et al. Long-term outcomes of hysterectomy with bilateral salpingo-oophorectomy: a systematic review and meta-analysis. Am J Obstet Gynecol. 2024; 230 (1): 44–57. https://doi.org/10.1016/j.ajog.2023.06.043.Emons G., Kim J.W., Weide K., et al. Endometrial Cancer Lymphadenectomy Trial (ECLAT) (pelvic and para-aortic lymphadenectomy in patients with stage I or II endometrial cancer with high risk of recurrence; AGO-OP.6). Int J Gynecol Cancer. 2021; 31 (7): 1075–9. https://doi.org/10.1136/ijgc-2021-002703.Emons G., Kim J.W., Weide K., et al. Endometrial Cancer Lymphadenectomy Trial (ECLAT) (pelvic and para-aortic lymphadenectomy in patients with stage I or II endometrial cancer with high risk of recurrence; AGO-OP.6). Int J Gynecol Cancer. 2021; 31 (7): 1075–9. https://doi.org/10.1136/ijgc-2021-002703.Segarra-Vidal B., Dinoi G., Zorrilla-Vaca A., et al. Minimally invasive compared with open hysterectomy in high-risk endometrial cancer. Obstet Gynecol. 2021; 138 (6): 828–37. https://doi.org/10.1097/AOG.0000000000004606.Segarra-Vidal B., Dinoi G., Zorrilla-Vaca A., et al. Minimally invasive compared with open hysterectomy in high-risk endometrial cancer. Obstet Gynecol. 2021; 138 (6): 828–37. https://doi.org/10.1097/AOG.0000000000004606.Mülkoğlu C., Ersever E.M., Çakıt B.D. Evaluation of incontinence and lymphedema in gynecological cancer patients along with their impact on the quality of life. Support Care Cancer. 2023; 31 (7): 437. https://doi.org/10.1007/s00520-023-07896-z.Mülkoğlu C., Ersever E.M., Çakıt B.D. Evaluation of incontinence and lymphedema in gynecological cancer patients along with their impact on the quality of life. Support Care Cancer. 2023; 31 (7): 437. https://doi.org/10.1007/s00520-023-07896-z.Mishra N., Singh N., Sachdeva M., Ghatage P. Sexual dysfunction in cervical cancer survivors: a scoping review. Womens Health Rep. 2021; 2 (1): 594–607. https://doi.org/10.1089/whr.2021.0035.Mishra N., Singh N., Sachdeva M., Ghatage P. Sexual dysfunction in cervical cancer survivors: a scoping review. Womens Health Rep. 2021; 2 (1): 594–607. https://doi.org/10.1089/whr.2021.0035.Nitecki R., Fu S., Lefkowits C., et al. Employment disruption following the diagnosis of endometrial cancer. Gynecol Oncol. 2021; 160 (1): 199–205. https://doi.org/10.1016/j.ygyno.2020.10.041.Nitecki R., Fu S., Lefkowits C., et al. Employment disruption following the diagnosis of endometrial cancer. Gynecol Oncol. 2021; 160 (1): 199–205. https://doi.org/10.1016/j.ygyno.2020.10.041.Nitecki R., Fu S., Jorgensen K.A., et al. Employment disruption among women with gynecologic cancers. Int J Gynecol Cancer. 2022; 32 (1): 69–78. https://doi.org/10.1136/ijgc-2021-002949.Nitecki R., Fu S., Jorgensen K.A., et al. Employment disruption among women with gynecologic cancers. Int J Gynecol Cancer. 2022; 32 (1): 69–78. https://doi.org/10.1136/ijgc-2021-002949.Xie Y., Ren Y., Niu C., et al. The impact of stigma on mental health and quality of life of infertile women: a systematic review. Front Psychol. 2023; 13: 1093459. https://doi.org/10.3389/fpsyg.2022.1093459.Xie Y., Ren Y., Niu C., et al. The impact of stigma on mental health and quality of life of infertile women: a systematic review. Front Psychol. 2023; 13: 1093459. https://doi.org/10.3389/fpsyg.2022.1093459.Boding S.A., Hutchinson A., Webb S.N. Factors that influence self-identity in women who have undergone gynecological cancer treatment. Womens Reprod Health. 2023; 10 (3): 402–19. https://doi.org/10.1080/23293691.2022.2124139.Boding S.A., Hutchinson A., Webb S.N. Factors that influence self-identity in women who have undergone gynecological cancer treatment. Womens Reprod Health. 2023; 10 (3): 402–19. https://doi.org/10.1080/23293691.2022.2124139.Tosic Golubovic S., Binic I., Krtinic D., et al. Risk factors and predictive value of depression and anxiety in cervical cancer patients. Medicina. 2022; 58 (4): 507. https://doi.org/10.3390/medicina58040507.Tosic Golubovic S., Binic I., Krtinic D., et al. Risk factors and predictive value of depression and anxiety in cervical cancer patients. Medicina. 2022; 58 (4): 507. https://doi.org/10.3390/medicina58040507.Garvey M. The association between dysbiosis and neurological conditions often manifesting with chronic pain. Biomedicines. 2023; 11 (3): 748. https://doi.org/10.3390/biomedicines11030748.Garvey M. The association between dysbiosis and neurological conditions often manifesting with chronic pain. Biomedicines. 2023; 11 (3): 748. https://doi.org/10.3390/biomedicines11030748.Lunde S., Nguyen H.T., Petersen K.K., et al. Chronic postoperative pain after hysterectomy for endometrial cancer: a metabolic profiling study. Mol Pain. 2020; 16: 1744806920923885. https://doi.org/10.1177/1744806920923885.Lunde S., Nguyen H.T., Petersen K.K., et al. Chronic postoperative pain after hysterectomy for endometrial cancer: a metabolic profiling study. Mol Pain. 2020; 16: 1744806920923885. https://doi.org/10.1177/1744806920923885.Рубрикатор клинических рекомендаций. Рак шейки матки. 2024. URL: https://cr.minzdrav.gov.ru/preview-cr/537_3 (дата обращения 20.01.2025).Clinical Guidelines Rubricator. Cervical Cancer. 2024. Available at: https://cr.minzdrav.gov.ru/preview-cr/537_3 (in Russ.) (accessed 20.01.2025).Рубрикатор клинических рекомендаций. Рак тела матки и саркомы матки. 2024. URL: https://cr.minzdrav.gov.ru/preview-cr/460_4 (дата обращения 20.01.2025).Clinical Guidelines Rubricator. Uterine body cancer and uterine sarcomas. 2024. Available at: https://cr.minzdrav.gov.ru/preview-cr/460_4 (in Russ.) (accessed 20.01.2025).Sun Y.S., Chen W.L., Wu W.T., Wang C.C. The fact of return to work in cervical cancer survivors and the impact of survival rate: an 11-year follow-up study. Int J Environ Res Public Health. 2021; 18 (20): 10703. https://doi.org/10.3390/ijerph182010703.Sun Y.S., Chen W.L., Wu W.T., Wang C.C. The fact of return to work in cervical cancer survivors and the impact of survival rate: an 11-year follow-up study. Int J Environ Res Public Health. 2021; 18 (20): 10703. https://doi.org/10.3390/ijerph182010703.Meixner E., Sandrini E., Hoeltgen L., et al. Return to work, fatigue and cancer rehabilitation after curative radiotherapy and radiochemotherapy for pelvic gynecologic cancer. Cancers. 2022; 14 (9): 2330. https://doi.org/10.3390/cancers14092330.Meixner E., Sandrini E., Hoeltgen L., et al. Return to work, fatigue and cancer rehabilitation after curative radiotherapy and radiochemotherapy for pelvic gynecologic cancer. Cancers. 2022; 14 (9): 2330. https://doi.org/10.3390/cancers14092330.Nakamura K., Masuyama H., Ida N., et al. Radical hysterectomy plus concurrent chemoradiation/radiation therapy is negatively associated with return to work in patients with cervical cancer. Int J Gynecol Cancer. 2017; 27 (1): 117–22. https://doi.org/10.1097/IGC.0000000000000840.Nakamura K., Masuyama H., Ida N., et al. Radical hysterectomy plus concurrent chemoradiation/radiation therapy is negatively associated with return to work in patients with cervical cancer. Int J Gynecol Cancer. 2017; 27 (1): 117–22. https://doi.org/10.1097/IGC.0000000000000840.Nachreiner N.M., Ghebre R.G., Virnig B.A., Shanley R. Early work patterns for gynaecological cancer survivors in the USA. Occup Med. 2012; 62 (1): 23–8. https://doi.org/10.1093/occmed/kqr177.Nachreiner N.M., Ghebre R.G., Virnig B.A., Shanley R. Early work patterns for gynaecological cancer survivors in the USA. Occup Med. 2012; 62 (1): 23–8. https://doi.org/10.1093/occmed/kqr177.Блинов Д.В., Солопова А.Г., Гамеева Е.В. и др. Возврат к трудовой деятельности после хирургического лечения рака шейки матки: изучение отдаленных результатов в течение 3 лет. Вестник восстановительной медицины. 2024; 23 (6): 54–61. https://doi.org/10.38025/2078-1962-2024-23-6-54-61.Blinov D.V., Solopova A.G., Gameeva E.V., et al. Resumption of employment after cervical cancer surgery: a 3-year follow-up study of long-term outcomes. Bulletin of Rehabilitation Medicine. 2024; 23 (6): 54–61 (in Russ.). https://doi.org/10.38025/2078-1962-2024-23-6-54-61.Бегович Ё., Байгалмаа Б., Солопова А.Г. и др. Качество жизни как критерий оценки эффективности реабилитационных программ у пациенток с болевой формой наружного генитального эндометриоза. Акушерство, гинекология и репродукция. 2023; 17 (1): 92–103. https://doi.org/10.17749/2313-7347/ob.gyn.rep.2023.391.Begovich E., Baigalmaa B., Solopova A.G., et al. Quality of life as a criterion for assessing the effectiveness of rehabilitation programs in patients with painful external genital endometriosis. Obstetrics, Gynecology and Reproduction. 2023; 17 (1): 92–103 (in Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2023.391.Бегович Ё., Солопова А.Г., Хлопкова С.В. и др. Качество жизни и особенности психоэмоционального статуса больных наружным генитальным эндометриозом. Акушерство, гинекология и репродукция. 2022; 16 (2): 122–33. https://doi.org/10.17749/2313-7347/ob.gyn.rep.2022.283.Begovich E., Solopova A.G., Khlopkova S.V., et al. Quality of life and psychoemotional status in patients with external genital endometriosis. Obstetrics, Gynecology and Reproduction. 2022; 16 (2): 122–33 (in Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2022.283.

The authors declare that there are no conflicts of interest present.