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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rehab</journal-id><journal-title-group><journal-title xml:lang="ru">Реабилитология</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Medical Rehabilitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2949-5873</issn><issn pub-type="epub">2949-5881</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2949-5873/rehabil.2025.53</article-id><article-id custom-type="elpub" pub-id-type="custom">rehab-121</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLES</subject></subj-group></article-categories><title-group><article-title>Интервальная гипокси-гипероксическая терапия в реабилитации пациентов с постковидным синдромом</article-title><trans-title-group xml:lang="en"><trans-title>Intermittent hypoxic-hyperoxic therapy in rehabilitation of patients with post-COVID syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2659-7998</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Торшин</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Torshin</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Торшин Иван Юрьевич, к.ф-м.н., к.х.н.  </p><p>ул. Вавилова, д. 44, корп. 2, Москва 119333 </p><p>WoS ResearcherID: C-7683-2018</p><p>Scopus Author ID: 7003300274 </p></bio><bio xml:lang="en"><p>Ivan Yu. Torshin, PhD </p><p>44 corp. 2 Vavilov Str., Moscow 119333 </p><p>WoS ResearcherID: C-7683-2018</p><p>Scopus Author ID: 7003300274 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5070-5450</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чучалин</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Chuchalin</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чучалин Александр Григорьевич, д.м.н., проф., академик РАН </p><p>ул. 1-я Леонова, д. 16, Москва 129226 </p></bio><bio xml:lang="en"><p>Alexander G. Chuchalin, Dr. Sci. Med., Prof., Academician of RAS </p><p>16 Pervaya Leonov Str., Moscow 129226 </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7663-710X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromova</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Громова Ольга Алексеевна, д.м.н., проф. </p><p>ул. Вавилова, д. 44, корп. 2, Москва 119333  </p><p>WoS ResearcherID: J-4946-2017</p><p>Scopus Author ID: 7003589812 </p></bio><bio xml:lang="en"><p>Olga A. Gromova, Dr. Sci. Med., Prof.</p><p>44 corp. 2 Vavilov Str., Moscow 119333   </p><p>WoS ResearcherID: J-4946-2017</p><p>Scopus Author ID: 7003589812</p></bio><email xlink:type="simple">unesco.gromova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральный исследовательский центр «Информатика и управление» Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Research Center “Computer Science and Control”, Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное автономное образовательное учреждение высшего образования «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>08</day><month>04</month><year>2026</year></pub-date><volume>3</volume><issue>3</issue><fpage>200</fpage><lpage>211</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Торшин И.Ю., Чучалин А.Г., Громова О.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Торшин И.Ю., Чучалин А.Г., Громова О.А.</copyright-holder><copyright-holder xml:lang="en">Torshin I.Y., Chuchalin A.G., Gromova O.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rehabilitology.com/jour/article/view/121">https://www.rehabilitology.com/jour/article/view/121</self-uri><abstract><p>С момента начала пандемии COVID-19 прошло уже более 5 лет, но вопросы реабилитации пациентов после перенесенной коронавирусной инфекции остаются актуальными. Так, в поисках новых методов реабилитации исследователи обратили внимание на интервальную гипокси-гипероксическую терапию (ИГГТ) как на средство восстановления утраченных физических и психологических резервов организма. Проведение ИГГТ способствует комплексной нормализации функций организма пациента путем воздействия на метаболические, иммунные процессы и антиоксидантную защиту. Многочисленные клинические исследования указывают на перспективность данного метода реабилитации, что подтверждается его эффективностью, безопасностью, сохранением достигнутого эффекта на протяжении 3–6 мес. Авторы рассмотренных в обзоре публикаций отмечают эффективность ИГГТ в лечении больных с сочетанной патологией. Однако ряд выявленных ограничений не позволяет масштабировать данный метод до стандартных протоколов реабилитации, что в совокупности с накопленными данными формирует запрос на проведение крупного многоцентрового исследования, в котором будет оценена эффективность и безопасность ИГГТ у пациентов с постковидным синдромом различных степеней тяжести.</p></abstract><trans-abstract xml:lang="en"><p>Over five years have passed since the COVID-19 outbreak, but the rehabilitation of coronavirus patients still remains a highly relevant issue. In the search for new rehabilitation approaches, researchers have turned their attention to intermittent hypoxic-hyperoxic therapy (IHHT) as a means of restoring impaired physical and psychological body reserves. IHHT promotes comprehensive recovery by modulating metabolic and immune processes as well as antioxidant defenses. Numerous clinical studies indicate the potential of this rehabilitation modality, which is supported by its efficacy, safety, and the preservation of achieved effects for three to six months. The reviewed publications report the IHHT effectiveness in patients with combined pathology. However, a number of identified limitations currently prevents this method from being scaled up to the level of standard rehabilitation protocols, which, together with the existing body of evidence, raises the need for a large multicenter study to evaluate the efficacy and safety of IHHT in patients with post‑COVID syndrome of varying severity.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>реабилитация</kwd><kwd>COVID-19</kwd><kwd>интервальная гипокси-гипероксическая терапия</kwd><kwd>постковидный синдром</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rehabilitation</kwd><kwd>COVID-19</kwd><kwd>intermittent hypoxic-hyperoxic therapy</kwd><kwd>post-COVID syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Filip R., Gheorghita Puscaselu R., Anchidin-Norocel L., et al. Global challenges to public health care systems during the COVID-19 pandemic: a review of pandemic measures and problems. J Pers Med. 2022; 12 (8): 1295. https://doi.org/10.3390/jpm12081295.</mixed-citation><mixed-citation xml:lang="en">Filip R., Gheorghita Puscaselu R., Anchidin-Norocel L., et al. Global challenges to public health care systems during the COVID-19 pandemic: a review of pandemic measures and problems. J Pers Med. 2022; 12 (8): 1295. https://doi.org/10.3390/jpm12081295.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Zangrillo A., Gattinoni L. Learning from mistakes during the pandemic: the Lombardy lesson. Intensive Care Med. 2020; 46 (8): 1622–3. https://doi.org/10.1007/s00134-020-06137-9.</mixed-citation><mixed-citation xml:lang="en">Zangrillo A., Gattinoni L. Learning from mistakes during the pandemic: the Lombardy lesson. Intensive Care Med. 2020; 46 (8): 1622–3. https://doi.org/10.1007/s00134-020-06137-9.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Ghosh S., Raghunath M., Sinha J.K. Navigating the commonality of healthcare failures: COVID-19 and conflict zones. Cureus. 2023; 15 (12): e50668. https://doi.org/10.7759/cureus.50668.</mixed-citation><mixed-citation xml:lang="en">Ghosh S., Raghunath M., Sinha J.K. Navigating the commonality of healthcare failures: COVID-19 and conflict zones. Cureus. 2023; 15 (12): e50668. https://doi.org/10.7759/cureus.50668.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Raphela T.D. Resilience and preparedness of hospitals for pandemics: lessons learned from COVID-19. Jamba. 2024; 16 (2): 1804. https://doi.org/10.4102/jamba.v16i2.1804.</mixed-citation><mixed-citation xml:lang="en">Raphela T.D. Resilience and preparedness of hospitals for pandemics: lessons learned from COVID-19. Jamba. 2024; 16 (2): 1804. https://doi.org/10.4102/jamba.v16i2.1804.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Liu Y., Funk S., Flasche S. The contribution of pre-symptomatic infection to the transmission dynamics of COVID-2019. Wellcome Open Res. 2020; 5: 58. https://doi.org/10.12688/wellcomeopenres.15788.1.</mixed-citation><mixed-citation xml:lang="en">Liu Y., Funk S., Flasche S. The contribution of pre-symptomatic infection to the transmission dynamics of COVID-2019. Wellcome Open Res. 2020; 5: 58. https://doi.org/10.12688/wellcomeopenres.15788.1.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Gao W., Lv J., Pang Y., Li L.M. Role of asymptomatic and pre-symptomatic infections in covid-19 pandemic. BMJ. 2021; 375: n2342. https://doi.org/10.1136/bmj.n2342.</mixed-citation><mixed-citation xml:lang="en">Gao W., Lv J., Pang Y., Li L.M. Role of asymptomatic and pre-symptomatic infections in covid-19 pandemic. BMJ. 2021; 375: n2342. https://doi.org/10.1136/bmj.n2342.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Marshall-Andon T., Walsh S., Berger-Gillam T., Pari A.A.A. Systematic review of post-COVID-19 syndrome rehabilitation guidelines. Integr Healthc J. 2023; 4 (1): e000100. https://doi.org/10.1136/ihj-2021-000100.</mixed-citation><mixed-citation xml:lang="en">Marshall-Andon T., Walsh S., Berger-Gillam T., Pari A.A.A. Systematic review of post-COVID-19 syndrome rehabilitation guidelines. Integr Healthc J. 2023; 4 (1): e000100. https://doi.org/10.1136/ihj-2021-000100.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Décary S., De Groote W., Arienti C., et al. Scoping review of rehabilitation care models for post COVID-19 condition. Bull World Health Organ. 2022; 100 (11): 676–88. https://doi.org/10.2471/BLT.22.288105.</mixed-citation><mixed-citation xml:lang="en">Décary S., De Groote W., Arienti C., et al. Scoping review of rehabilitation care models for post COVID-19 condition. Bull World Health Organ. 2022; 100 (11): 676–88. https://doi.org/10.2471/BLT.22.288105.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Manhas K.P., O’Connell P., Krysa J., et al. Development of a novel care rehabilitation pathway for post-COVID conditions (long COVID) in a provincial health system in Alberta, Canada. Phys Ther. 2022; 102 (9): pzac090. https://doi.org/10.1093/ptj/pzac090.</mixed-citation><mixed-citation xml:lang="en">Manhas K.P., O’Connell P., Krysa J., et al. Development of a novel care rehabilitation pathway for post-COVID conditions (long COVID) in a provincial health system in Alberta, Canada. Phys Ther. 2022; 102 (9): pzac090. https://doi.org/10.1093/ptj/pzac090.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">van der Feltz-Cornelis C., Heightman M., Allsopp G. Learning from long COVID: integrated care for multiple long-term conditions. Br J Gen Pract. 2023; 73 (730): 196–7. https://doi.org/10.3399/bjgp23X732561.</mixed-citation><mixed-citation xml:lang="en">van der Feltz-Cornelis C., Heightman M., Allsopp G. Learning from long COVID: integrated care for multiple long-term conditions. Br J Gen Pract. 2023; 73 (730): 196–7. https://doi.org/10.3399/bjgp23X732561.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Рубрикатор клинических рекомендаций. Коронавирусная инфекция COVID-19. 2025. URL: https://cr.minzdrav.gov.ru/view-cr/1024_1 (дата обращения 02.09.2025).</mixed-citation><mixed-citation xml:lang="en">Рубрикатор клинических рекомендаций. Коронавирусная инфекция COVID-19. 2025. URL: https://cr.minzdrav.gov.ru/view-cr/1024_1 (дата обращения 02.09.2025). Rubricator of clinical guidelines. Coronavirus infection COVID-19. 2025. Available at: https://cr.minzdrav.gov.ru/view-cr/1024_1 (in Russ.) (accessed 02.09.2025).</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">McClelland R.D., Lin Y.C.J., Culp T.N., et al. The domestication of SARS-CoV-2 into a seasonal infection by viral variants. Front Microbiol. 2023; 14: 1289387. https://doi.org/10.3389/fmicb.2023.1289387.</mixed-citation><mixed-citation xml:lang="en">McClelland R.D., Lin Y.C.J., Culp T.N., et al. The domestication of SARS-CoV-2 into a seasonal infection by viral variants. Front Microbiol. 2023; 14: 1289387. https://doi.org/10.3389/fmicb.2023.1289387.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">da Costa V.G., Saivish M.V., Santos D.E.R., et al. Comparative epidemiology between the 2009 H1N1 influenza and COVID-19 pandemics. J Infect Public Health. 2020; 13 (12): 1797–804. https://doi.org/10.1016/j.jiph.2020.09.023.</mixed-citation><mixed-citation xml:lang="en">da Costa V.G., Saivish M.V., Santos D.E.R., et al. Comparative epidemiology between the 2009 H1N1 influenza and COVID-19 pandemics. J Infect Public Health. 2020; 13 (12): 1797–804. https://doi.org/10.1016/j.jiph.2020.09.023.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Канорский С.Г. Постковидный синдром: распространенность и патогенез органных поражений, направления коррекции. Систематический обзор. Кубанский научный медицинский вестник. 2021; 28 (6): 90–116. https://doi.org/10.25207/1608-6228-2021-28-6-90-116.</mixed-citation><mixed-citation xml:lang="en">Kanorskii S.G. Post-COVID syndrome: prevalence, organ pathogenesis and routes of correction. A systematic review. Kuban Scientific Medical Bulletin. 2021; 28 (6): 90–116 (in Russ.). https://doi.org/10.25207/1608-6228-2021-28-6-90-116.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Carfì A., Bernabei R., Landi F., et al. Persistent symptoms in patients after acute COVID-19. JAMA. 2020; 324 (6): 603–5. https://doi.org/10.1001/jama.2020.12603.</mixed-citation><mixed-citation xml:lang="en">Carfì A., Bernabei R., Landi F., et al. Persistent symptoms in patients after acute COVID-19. JAMA. 2020; 324 (6): 603–5. https://doi.org/10.1001/jama.2020.12603.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Tenforde M.W., Kim S.S., Lindsell C.J., et al. Symptom duration and risk factors for delayed return to usual health among outpatients with COVID-19 in a multistate health care systems network – United States, March–June 2020. MMWR Morb Mortal Wkly Rep. 2020; 69 (30): 993–8. https://doi.org/10.15585/mmwr.mm6930e1.</mixed-citation><mixed-citation xml:lang="en">Tenforde M.W., Kim S.S., Lindsell C.J., et al. Symptom duration and risk factors for delayed return to usual health among outpatients with COVID-19 in a multistate health care systems network – United States, March–June 2020. MMWR Morb Mortal Wkly Rep. 2020; 69 (30): 993–8. https://doi.org/10.15585/mmwr.mm6930e1.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Carvalho-Schneider C., Laurent E., Lemaignen A., et al. Follow-up of adults with noncritical COVID-19 two months after symptom onset. Clin Microbiol Infect. 2021; 27 (2): 258–63. https://doi.org/10.1016/j.cmi.2020.09.052.</mixed-citation><mixed-citation xml:lang="en">Carvalho-Schneider C., Laurent E., Lemaignen A., et al. Follow-up of adults with noncritical COVID-19 two months after symptom onset. Clin Microbiol Infect. 2021; 27 (2): 258–63. https://doi.org/10.1016/j.cmi.2020.09.052.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Chopra V., Flanders S.A., O’Malley M., et al. Sixty-day outcomes among patients hospitalized with COVID-19. Ann Intern Med. 2021; 174 (4): 576–8. https://doi.org/10.7326/M20-5661.</mixed-citation><mixed-citation xml:lang="en">Chopra V., Flanders S.A., O’Malley M., et al. Sixty-day outcomes among patients hospitalized with COVID-19. Ann Intern Med. 2021; 174 (4): 576–8. https://doi.org/10.7326/M20-5661.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Halpin S.J., McIvor C., Whyatt G., et al. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: a crosssectional evaluation. J Med Virol. 2021; 93 (2): 1013–22. https://doi.org/10.1002/jmv.26368.</mixed-citation><mixed-citation xml:lang="en">Halpin S.J., McIvor C., Whyatt G., et al. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: a crosssectional evaluation. J Med Virol. 2021; 93 (2): 1013–22. https://doi.org/10.1002/jmv.26368.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Sk Abd Razak R., Ismail A., Abdul Aziz A.F., et al. Post-COVID syndrome prevalence: a systematic review and meta-analysis. BMC Public Health. 2024; 24 (1): 1785. https://doi.org/10.1186/s12889-024-19264-5.</mixed-citation><mixed-citation xml:lang="en">Sk Abd Razak R., Ismail A., Abdul Aziz A.F., et al. Post-COVID syndrome prevalence: a systematic review and meta-analysis. BMC Public Health. 2024; 24 (1): 1785. https://doi.org/10.1186/s12889-024-19264-5.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Arjun M.C., Singh A.K., Pal D., et al. Characteristics and predictors of long COVID among diagnosed cases of COVID-19. PLoS One. 2022; 17 (12): e0278825. https://doi.org/10.1371/journal.pone.0278825.</mixed-citation><mixed-citation xml:lang="en">Arjun M.C., Singh A.K., Pal D., et al. Characteristics and predictors of long COVID among diagnosed cases of COVID-19. PLoS One. 2022; 17 (12): e0278825. https://doi.org/10.1371/journal.pone.0278825.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Kim Y., Bitna-Ha, Kim S.W., et al. Post-acute COVID-19 syndrome in patients after 12 months from COVID-19 infection in Korea. BMC Infect Dis. 2022; 22 (1): 93. https://doi.org/10.1186/s12879-022-07062-6.</mixed-citation><mixed-citation xml:lang="en">Kim Y., Bitna-Ha, Kim S.W., et al. Post-acute COVID-19 syndrome in patients after 12 months from COVID-19 infection in Korea. BMC Infect Dis. 2022; 22 (1): 93. https://doi.org/10.1186/s12879-022-07062-6.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">McElvaney O.J., McEvoy N.L., McElvaney O.F., et al. Characterization of the inflammatory response to severe COVID-19 illness. Am J Respir Crit Care Med. 2020; 202 (6): 812–21. https://doi.org/10.1164/rccm.202005-1583OC.</mixed-citation><mixed-citation xml:lang="en">McElvaney O.J., McEvoy N.L., McElvaney O.F., et al. Characterization of the inflammatory response to severe COVID-19 illness. Am J Respir Crit Care Med. 2020; 202 (6): 812–21. https://doi.org/10.1164/rccm.202005-1583OC.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Tang N., Li D., Wang X., Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020; 18 (4): 844–7. https://doi.org/10.1111/jth.14768.</mixed-citation><mixed-citation xml:lang="en">Tang N., Li D., Wang X., Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020; 18 (4): 844–7. https://doi.org/10.1111/jth.14768.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Hu B., Guo H., Zhou P., Shi Z.L. Characteristics of SARS-CoV-2 and COVID-19. Nat Rev Microbiol. 2021; 19 (3): 141–54. https://doi. org/10.1038/s41579-020-00459-7.</mixed-citation><mixed-citation xml:lang="en">Hu B., Guo H., Zhou P., Shi Z.L. Characteristics of SARS-CoV-2 and COVID-19. Nat Rev Microbiol. 2021; 19 (3): 141–54. https://doi. org/10.1038/s41579-020-00459-7.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Lu R., Zhao X., Li J., et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020; 395 (10224): 565–74. https://doi.org/10.1016/S0140-6736(20)30251-8.</mixed-citation><mixed-citation xml:lang="en">Lu R., Zhao X., Li J., et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020; 395 (10224): 565–74. https://doi.org/10.1016/S0140-6736(20)30251-8.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Shang J., Ye G., Shi K., et al. Structural basis of receptor recognition by SARS-CoV-2. Nature. 2020; 581 (7807): 221–4. https://doi.org/10.1038/s41586-020-2179-y.</mixed-citation><mixed-citation xml:lang="en">Shang J., Ye G., Shi K., et al. Structural basis of receptor recognition by SARS-CoV-2. Nature. 2020; 581 (7807): 221–4. https://doi.org/10.1038/s41586-020-2179-y.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Inoue S., Hatakeyama J., Kondo Y., et al. Post-intensive care syndrome: its pathophysiology, prevention, and future directions. Acute Med Surg. 2019; 6 (3): 233–46. https://doi.org/10.1002/ams2.415.</mixed-citation><mixed-citation xml:lang="en">Inoue S., Hatakeyama J., Kondo Y., et al. Post-intensive care syndrome: its pathophysiology, prevention, and future directions. Acute Med Surg. 2019; 6 (3): 233–46. https://doi.org/10.1002/ams2.415.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Hosey M.M., Needham D.M. Survivorship after COVID-19 ICU stay. Nat Rev Dis Primers. 2020; 6 (1): 60. https://doi.org/10.1038/s41572-020-0201-1.</mixed-citation><mixed-citation xml:lang="en">Hosey M.M., Needham D.M. Survivorship after COVID-19 ICU stay. Nat Rev Dis Primers. 2020; 6 (1): 60. https://doi.org/10.1038/s41572-020-0201-1.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Gutzeit J., Weiß M., Nürnberger C., et al. Definitions and symptoms of the post-COVID syndrome: an updated systematic umbrella review. Eur Arch Psychiatry Clin Neurosci. 2025; 275 (1): 129–40. https://doi.org/10.1007/s00406-024-01868-y.</mixed-citation><mixed-citation xml:lang="en">Gutzeit J., Weiß M., Nürnberger C., et al. Definitions and symptoms of the post-COVID syndrome: an updated systematic umbrella review. Eur Arch Psychiatry Clin Neurosci. 2025; 275 (1): 129–40. https://doi.org/10.1007/s00406-024-01868-y.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Петрова М.С. Комплексный подход в реабилитации пациентов с COVID-19. (Oбзор литературы). Вопросы курортологии, физиотерапии и лечебной физической культуры. 2024; 101 (3): 48–55. https://doi.org/10.17116/kurort202410103148.</mixed-citation><mixed-citation xml:lang="en">Petrova M.S. Comprehensive approach to rehabilitation of patients with COVID-19. (A literature review). Problems of Balneology, Physiotherapy and Exercise Therapy. 2024; 101 (3): 48–55 (in Russ.). https://doi.org/10.17116/kurort202410103148.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Jimeno-Almazán A., Franco-López F., Buendía-Romero Á., et al. Rehabilitation for post-COVID-19 condition through a supervised exercise intervention: a randomized controlled trial. Scand J Med Sci Sports. 2022; 32 (12): 1791–801. https://doi.org/10.1111/sms.14240.</mixed-citation><mixed-citation xml:lang="en">Jimeno-Almazán A., Franco-López F., Buendía-Romero Á., et al. Rehabilitation for post-COVID-19 condition through a supervised exercise intervention: a randomized controlled trial. Scand J Med Sci Sports. 2022; 32 (12): 1791–801. https://doi.org/10.1111/sms.14240.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Ласынова Г.Х., Лакман И.А., Гареева Д.Ф. и др. Реабилитация пациентов после новой коронавирусной инфекции (COVID-19) и ee влияние на сердечно-сосудистые конечные точки: propensity score matching анализ. Российский кардиологический журнал. 2023; 28 (4S): 5630. https://doi.org/10.15829/1560-4071-2023-5630.</mixed-citation><mixed-citation xml:lang="en">Lasynova G.Kh., Lakman I.A., Gareeva D.F., et al. Rehabilitation of COVID-19 convalescents and its impact on cardiovascular endpoints: propensity score matching analysis. Russian Journal of Cardiology. 2023; 28 (4S): 5630 (in Russ.). https://doi.org/10.15829/1560-4071-2023-5630.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Залетова Т.С. Интервальная гипоксическая терапия в кардиологии и диетологии. Медицина. Социология. Философия. Прикладные исследования. 2022; 4: 32–4.</mixed-citation><mixed-citation xml:lang="en">Zaletova T.S. Interval hypoxic therapy in cardiology and dietetics. Medicine. Sociology. Philosophy. Applied Research. 2022; 4: 32–4 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Мирютова Н.Ф., Груздева Д.А. Область применения, механизмы действия и эффективность гипербарической оксигенации в восстановительной медицине. Реабилитология. 2025; 3 (1): 36–50. https://doi.org/10.17749/2949-5873/rehabil.2025.38.</mixed-citation><mixed-citation xml:lang="en">Miryutova N.F., Gruzdeva D.A. Hyperbaric oxygenation in rehabilitation medicine: application, action mechanisms, and effectiveness. Reabilitologia / Journal of Medical Rehabilitation. 2025; 3 (1): 36–50 (in Russ.). https://doi.org/10.17749/2949-5873/rehabil.2025.38.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Cannellotto M., Yasells García A., Landa M.S. Hyperoxia: effective mechanism of hyperbaric treatment at mild-pressure. Int J Mol Sci. 2024; 25 (2): 777. https://doi.org/10.3390/ijms25020777.</mixed-citation><mixed-citation xml:lang="en">Cannellotto M., Yasells García A., Landa M.S. Hyperoxia: effective mechanism of hyperbaric treatment at mild-pressure. Int J Mol Sci. 2024; 25 (2): 777. https://doi.org/10.3390/ijms25020777.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Мизиев И.А., Махов М.Х., Сабанчиева Ж.Х. и др. Оценка непосредственного влияния нормобарической интервальной гипоксической тренировки на субъективное состояние пациентов с хроническим простатитом. Главный врач Юга России. 2025; 2: 44–8.</mixed-citation><mixed-citation xml:lang="en">Miziev I.A., Makhov M.Kh., Sabanchieva Zh.Kh., et al. Assessment of the direct influence of normobaric interval hypoxic training on the subjective state of patients with chronic prostatitis. Glavnyy vrach Yuga Rossii. 2025; 2: 44–8 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Ильина А.А., Петрова М.В., Ильин Д.В. и др. Применение гипоксигиперокситерапии в клинической практике: перспективы использования в нейрореабилитации (обзор литературы). Вестник анестезиологии и реаниматологии. 2025; 22 (6): 128–37. https://doi.org/10.24884/2078-5658-2025-22-6-128-137.</mixed-citation><mixed-citation xml:lang="en">Ilyina A.A., Petrova M.V., Ilyin D.V., et al. Application of intermittent hypoxia-hyperoxia therapy in clinical practice: perspectives for use in neurorehabilitation (literature review). Messenger of Anesthesiology and Resuscitation. 2025; 22 (6): 128–37 (in Russ.). https://doi.org/10.24884/2078-5658-2025-22-6-128-137.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Иванова Г.Е., Суворов А.Ю., Бушкова Ю.В. и др. Использование интервальной нормобарической гипокси-гиперокситерапии в реабилитации пациентов с острым нарушением мозгового кровообращения (промежуточные результаты исследования). Вестник восстановительной медицины. 2018; 3: 115–22.</mixed-citation><mixed-citation xml:lang="en">Ivanova G.E., Suvorov A.U., Bushkova J.V., et al. Normobaric interval hypoxia-hyperoxic therapy (ihht) in the process of medical rehabilitation of patients after stroke. Bulletin of Rehabilitation Medicine. 2018; 3: 115–22 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Орлова Е.В., Лямина Н.П., Скоробогатых Н.В., Погонченкова И.В. Интервальная гипокси-гипероксическая терапия в комплексной реабилитации пациентов с остеоартритом. Практическая медицина. 2022; 20 (4): 81–4. https://doi.org/10.32000/2072-1757-2022-4-81-84.</mixed-citation><mixed-citation xml:lang="en">Orlova E.V., Lyamina N.P., Skorobogatyth N.V., Pogonchenkova I.V. Interval hypoxic-hyperoxic therapy in complex rehabilitation of patients with osteoarthritis. Practical Medicine. 2022; 20 (4): 81–4 (in Russ.). https://doi.org/10.32000/2072-1757-2022-4-81-84.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Лямина Н.П., Орлова Е.В., Скоробогатых Н.В., Ксенофонтова И.В. Индивидуально дозированная гипокси-гиперокситерапия в программах реабилитации кардиологических пациентов с мультиморбидной патологией. Вопросы курортологии, физиотерапии и лечебной физической культуры. 2022; 99 (5-2): 37–8.</mixed-citation><mixed-citation xml:lang="en">Lyamina N.P., Orlova E.V., Skorobogatyth N.V., Ksenofontova I.V. Individually dosed hypoxy-hyperoxytherapy in rehabilitation programs for cardiac patients with multimorbid pathology. Problems of Balneology, Physiotherapy, and Exercise Therapy. 2022; 99 (5-2): 37–8 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Орлова Е.В., Лямина Н.П., Скоробогатых Н.В., Ксенофонтова И.В. Эффективность интервальной гипокси-гиперокситерапии в реабилитации пациентов со скелетно-мышечной неспецифической болью в нижней части спины: результаты рандомизированного плацебо-контролируемого исследования. Физическая и реабилитационная медицина, медицинская реабилитация. 2024; 6 (2): 98–108. https://doi.org/10.36425/rehab630118.</mixed-citation><mixed-citation xml:lang="en">Orlova E.V., Lyamina N.P., Skorobogatyth N.V., Ksenofontova I.V. Efficiency of interval hypoxia-hyperoxytherapy in the rehabilitation of patients with nonspecific musculosceletal low back pain: results of а randomized placebo-controlled study. Physical and Rehabilitation Medicine, Medical Rehabilitation. 2024; 6 (2): 98–108 (in Russ.). https://doi.org/10.36425/rehab630118.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Андреева А.В., Якушин С.С. Влияние интервальных гипоксигипероксических тренировок на процесс реабилитации у пожилых пациентов с инфарктом миокарда и хронической сердечной недостаточностью (предварительные результаты). Терапия. 2025; 3: 71–80. https://doi.org/10.18565/therapy. 2025.3.71-80.</mixed-citation><mixed-citation xml:lang="en">Andreeva A.V., Yakushin S.S. Influence of interval hypoxi-hyperoxic training at the rehabilitation process in elderly patients with myocardial infarction and chronic heart failure (preliminary results). Therapy. 2025; 11 (3): 71–80 (in Russ.). https://doi.org/10.18565/therapy.2025.3.71-80.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Glazachev O.S., Kryzhanovskaya S.Y., Zapara M.A., et al. Safety and efficacy of intermittent hypoxia conditioning as a new rehabilitation/ secondary prevention strategy for patients with cardiovascular diseases: a systematic review and meta-analysis. Curr Cardiol Rev. 2021; 17 (6): e051121193317. https://doi.org/10.2174/1573403X17666210514005235.</mixed-citation><mixed-citation xml:lang="en">Glazachev O.S., Kryzhanovskaya S.Y., Zapara M.A., et al. Safety and efficacy of intermittent hypoxia conditioning as a new rehabilitation/ secondary prevention strategy for patients with cardiovascular diseases: a systematic review and meta-analysis. Curr Cardiol Rev. 2021; 17 (6): e051121193317. https://doi.org/10.2174/1573403X17666210514005235.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Tuter D.S., Kopylov P.Y., Syrkin A.L., et al. Intermittent systemic hypoxic–hyperoxic training for myocardial protection in patients undergoing coronary artery bypass surgery: first results from a singlecentre, randomised controlled trial. Open Heart. 2018; 5 (2): e000891. https://doi.org/10.1136/openhrt-2018-000891.</mixed-citation><mixed-citation xml:lang="en">Tuter D.S., Kopylov P.Y., Syrkin A.L., et al. Intermittent systemic hypoxic–hyperoxic training for myocardial protection in patients undergoing coronary artery bypass surgery: first results from a singlecentre, randomised controlled trial. Open Heart. 2018; 5 (2): e000891. https://doi.org/10.1136/openhrt-2018-000891.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Glazachev O., Kopylov P., Susta D., et al. Adaptations following an intermittent hypoxia-hyperoxia training in coronary artery disease patients: a controlled study. Clin Cardiol. 2017; 40 (6): 370–6. https://doi.org/10.1002/clc.22670.</mixed-citation><mixed-citation xml:lang="en">Glazachev O., Kopylov P., Susta D., et al. Adaptations following an intermittent hypoxia-hyperoxia training in coronary artery disease patients: a controlled study. Clin Cardiol. 2017; 40 (6): 370–6. https://doi.org/10.1002/clc.22670.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Orlova E., Lyamina N., Pogonchenkova I., Skorobogatykh N. Pos1453 interval hypoxic-hyperoxic training in rehabilitation of patients with osteoarthritis and post-covid syndrome. Ann Rheum Dis. 2022; 81 (Suppl. 1): 1071. https://doi.org/10.1136/annrheumdis-2022-eular.3861.</mixed-citation><mixed-citation xml:lang="en">Orlova E., Lyamina N., Pogonchenkova I., Skorobogatykh N. Pos1453 interval hypoxic-hyperoxic training in rehabilitation of patients with osteoarthritis and post-covid syndrome. Ann Rheum Dis. 2022; 81 (Suppl. 1): 1071. https://doi.org/10.1136/annrheumdis-2022-eular.3861.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Орлова Е.В., Лямина Н.П., Скоробогатых Н.В., Погонченкова И.В. Клиническая эффективность индивидуально дозированной интервальной гипокси-гипероксической терапии у пациентов с остеоартритом, имеющих постковидный синдром. Вестник восстановительной медицины. 2022; 21 (2): 6–16. https://doi.org/10.38025/2078-1962-2022-21-2-6-16.</mixed-citation><mixed-citation xml:lang="en">Orlova E.V., Lyamina N.P., Skorobogatyth N.V., Pogonchenkova I.V. Сlinical efficacy of individually dosed intermittent hypoxia-hyperoxic therapy in osteoarthritis patients with post-covid syndrome. Bulletin of Rehabilitation Medicine. 2022; 21 (2): 6–16 (in Russ.). https://doi.org/10.38025/2078-1962-2022-21-2-6-16.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Doehner W., Fischer A., Alimi B., et al. Intermittent hypoxic-hyperoxic training during inpatient rehabilitation improves exercise capacity and functional outcome in patients with long covid: results of a controlled clinical pilot trial. J Cachexia Sarcopenia Muscle. 2024; 15 (6): 2781–91. https://doi.org/10.1002/jcsm.13628.</mixed-citation><mixed-citation xml:lang="en">Doehner W., Fischer A., Alimi B., et al. Intermittent hypoxic-hyperoxic training during inpatient rehabilitation improves exercise capacity and functional outcome in patients with long covid: results of a controlled clinical pilot trial. J Cachexia Sarcopenia Muscle. 2024; 15 (6): 2781–91. https://doi.org/10.1002/jcsm.13628.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Воловец С.А., Цыганова Т.Н., Бадалов Н.Г. Эффективность гипогипероксических тренировок в медицинской реабилитации пациентов, перенeсших COVID-19. Физиотерапия, бальнеология и реабилитация. 2022; 21 (1): 35–46. https://doi.org/10.17816/rjpbr109501.</mixed-citation><mixed-citation xml:lang="en">Volovets S.A., Tsyganova T.N., Badalov N.G. The effectiveness of hypohyperoxic training in the medical rehabilitation of patients who have undergone COVID-19. Russian Journal of Physiotherapy, Balneology and Rehabilitation. 2022; 21 (1): 35–46 (in Russ.). https://doi.org/10.17816/rjpbr109501.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Лямина Н.П., Лямина С.В., Скоробогатых Н.В. и др. Управляемая гипокси-гиперокситерапия как компонент таргетного подхода в реабилитации пациентов с мультиморбидной патологией: одноцентровое рандомизированное плацебо-контролируемое проспективное исследование. Физическая и реабилитационная медицина, медицинская реабилитация. 2023; 5 (4): 279–88. https://doi.org/10.36425/rehab608182.</mixed-citation><mixed-citation xml:lang="en">Lyamina N.P., Lyamina S.V., Skorobogatyth N.V., et al. Controlled hypoxia-hyperoxytherapy as a component of a targeted approach in the rehabilitation of patients with multimorbidity: a single-center, randomized, placebo-controlled, prospective study. Physical and Rehabilitation Medicine, Medical Rehabilitation. 2023; 5 (4): 279–88 (in Russ.). https://doi.org/10.36425/rehab608182.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Kapel J.S., Stokholm R., Elmengaard B., et al. Individualized algorithmbased intermittent hypoxia improves quality of life in patients suffering from long-term sequelae after COVID-19 infection. J Clin Med. 2025; 14 (5): 1590. https://doi.org/10.3390/jcm14051590.</mixed-citation><mixed-citation xml:lang="en">Kapel J.S., Stokholm R., Elmengaard B., et al. Individualized algorithmbased intermittent hypoxia improves quality of life in patients suffering from long-term sequelae after COVID-19 infection. J Clin Med. 2025; 14 (5): 1590. https://doi.org/10.3390/jcm14051590.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Аль-Сунаа Р.С. Индивидуально дозированная гипоксигипероксическая терапия как инновационный метод реабилитации пациентов с постковидным синдромом. Наука и спорт: современные тенденции. 2025; 13 (2): 8–13. https://doi.org/10.36028/2308-8826-2025-13-2-8-13.</mixed-citation><mixed-citation xml:lang="en">Al-Sunaa R.S. Individually dosed hypoxi-hyperoxicous therapy as an innovative method of rehabilitation of patients with post-COVID syndrome. Science and Sports: Modern Trends. 2025; 13 (2): 8–13 (in Russ.). https://doi.org/10.36028/2308-8826-2025-13-2-8-13.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Карелова Н.Ю., Поддубный Д.В., Ларина А.В. Эффективность индивидуально дозированной нормобарической интервальной гипокси-гиперокситерапии в комплексной реабилитации пациентов после перенесенной коронавирусной пневмонии. Бюллетень медицинской науки. 2024; 2: 91–6. https://doi.org/10.31684/25418475-2024-2-91.</mixed-citation><mixed-citation xml:lang="en">Karelova N.Yu., Poddubny D.V., Larina A.V. Enhancing patient rehabilitation post-coronavirus pneumonia through individually dosed normobaric interval hypoxic hyperoxygenation therapy. Bulleten medicinskoj nauki. 2024; 2: 91–6 (in Russ.). https://doi.org/10.31684/25418475-2024-2-91.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Reuner M., Krehbiel J., Rech J., et al. Utilization frequency and patientreported effectiveness of symptomatic therapies in post-COVID syndrome. BMC Public Health. 2024; 24 (1): 2577. https://doi.org/10.1186/s12889-024-19951-3.</mixed-citation><mixed-citation xml:lang="en">Reuner M., Krehbiel J., Rech J., et al. Utilization frequency and patientreported effectiveness of symptomatic therapies in post-COVID syndrome. BMC Public Health. 2024; 24 (1): 2577. https://doi.org/10.1186/s12889-024-19951-3.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Бралюк М.А., Акинина Е.Г., Воронова О.А. Анализ результатов использования нормобарической интервальной гипоксигипероксической тренировки у больных с постковидным синдромом. Главный врач Юга России. 2022; 1: 37–40.</mixed-citation><mixed-citation xml:lang="en">Bralyuk M.A., Akinina E.G., Voronova O.A. Analysis of the results of using normobaric interval hypoxic-hyperoxic training in patients with postCOVID syndrome. Glavnyy vrach Yuga Rossii. 2022; 1: 37–40 (in Russ.).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
